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About us

Shandong Shining Pharm Co., Ltd. is Investment and holding by a natural person, sets up three R&D Centers under Shining Pharm: Jinan Synovel Laboratory Co.,Ltd., Tianjin Chemlike Scientific Co.,Ltd. and Nanjing Leizheng Pharm Co.,Ltd. Export agent: Taizhou Crene Biotechnology Co.,Ltd.  Our manufactory Located in Ningyang Fine Chemical Industry Park, Tai’an ,Shangdong province.

Shandong Shining Pharm is a high-tech manufactory, which is committed to producing high quality pharmaceutical intermediates, promoting innovation in API technology and provide customized services for global pharmaceutical companies, dedicates itself on research, develop and industrialize of high-end intermediates & API.   We have three R&D centers from Ji’nan, Tianjin and Nanjing, more than 40 R&D staff including 5 doctors, 20 masters and 18 synthesis assistants, along with their unique advantages in the product development, pilot and process optimization, of total hundred employees. Our products are highly praised by global customers as we are Closed cooperation with domestic pharmaceutical companies, with International market of India by intermediates, South American by APIs and actively develop the European and American market, cooperated with customers to DMF registration.

Shandong Shining Pharm bought the land with 40 mu (around 30000 square meter) in Ningyang Fine Chemical Industry Park, Tai’an., which is a provincial chemical industry park, established a high standard new manufactory, is about to set up cGMP quality system. Our new plant including 500㎡ analysis laboratories equipped with HPLC, LC-MS, GC and other analytical facilities, one pilot and four mass production workshop, the total reaction capacity can reach 35000L which can meet commercial production demands from kilos to hundreds of tons, is perfect for analysis and production.

Shandong Shining Pharm provides the high-level products and the most reasonable price for our Partners. Our main products of intermediates:  Idelalisib ints, Tedizolid ints, Afatinib ints, Nintedanib ints, Lenvatinib ints  Trifluridine( TAS-102)ints, etc.

“Social commitment, Professional services, Benefits society, Create better life” is Shandong Shining Pharm philosophy, Shandong Shining Pharm sincerely welcome global partners to get win-win cooperation, create a bright future!

Products list

Main products:AfatinibAfatinib dimaleate7-Fluoro-6-nitro-4-hydroxyquinazolineN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinaminen-(3-chloro-4-fluorophenyl)-6-nitro-7-(((3s)-tetrahydro-3-furanyl)oxy)-4-quinazolinamineN4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine(s)-(+)-3-hydroxytetrahydrofuran;(s)-(+)-tetrahydro-3-furanoltrans-4-dimethylaminocrotonic acid hydrochloride;(e)-4-(dimethylamino)-2-butenoic acid hydrochlorideIdelalisib(CAL-101)[(1S)-1-(5-Fluoro-3,4-dihydro-4-oxo-3-phenyl-2-quinazolinyl)propyl]carbamic acid 1,1-dimethylethyl ester(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-oneboc-l-2-aminobutyric acid2-fluoro-6-nitro-n-phenylbenzamide2-amino-5-fluoro-n-phenylbenzamide2-aMino-6-fluoro-N-phenylbenzaMide hydrochlorideTedizolid phosphateTedizolidn-(3-fluoro-4-(6-(2-methyl-2h-tetrazol-5-yl)-3-pyridinyl)phenyl)carbamic acid phenylmethyl ester5-bromo-2-(2-methyl-2h-tetrazol-5-yl)pyridine;2-(2-methyl-5-tetrazolyl)-5-bromopyridine(5r)-3-(4-bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one2-(2-methyl-2h-tetrazol-5-yl)pyridine-5-boronic acid pinacol ester;2-(2-methyl-2h-tetrazol-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineNintedanib (BIBF 1120)Nintedanib Ethanesulfonate Saltmethyl 2-oxoindole-6-carboxylate;6-methoxycarbonyl-2-oxindole; oxindole-6-carboxylic acid methyl esterN-(4-Aminophenyl)-N,4-dimethyl-1-piperazineacetamideN-Methyl-4-nitroaniline(3e)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1h-indole-6-carboxylic acid methyl estertrimethyl orthobenzoateLesinurad(RDEA594)3-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-5-thiol4-Cyclopropyl-1-naphthalenamine hydrochloride (1:1)1-cyclopropyl-4-isothiocyanatonaphthalene4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thioneMethyl 2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetateLenvatinib (E7080)Lenvatinib Mesylate4-chloro-7-methoxyquinoline-6-carboxamide1,4-dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl esterMethyl 4-chloro-7-methoxyquinoline-6-carboxylate4-amino-3-chlorophenolIbrutinib(PCI-32765)(r)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1h-pyrazolo(3,4-d)pyrimidin-4-amine3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-4-amine3-amino-4-cyano-5-(4-phenoxyphenyl)pyrazole(S)-1-Boc-3-hydroxypiperidinePalbociclib (PD0332991)tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-oneMacitentan4,6-dichloro-5-(4-bromophenyl)pyrimidinen-propylsulfamide;propylsulfamiden-propyl-sulfamide potassium saltn-propylsulfamide sodium saltn1-(2-(dimethylamino)ethyl)-5-methoxy-n1-methyl-n4-(4-(1-methyl-1h-indol-3-yl)-2-pyrimidinyl)-1,2,4-benzenetriamineN1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-2-nitro-1,4-benzenediaminen-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1h-indol-3-yl)-2-pyrimidinamine4-fluoro-2-methoxy-5-nitroaniline3-(2-chloro-4-pyrimidinyl)-1-methyl-1h-indoleNeratinib(HKI-272)3-Chloro-4-[(pyridin-2-yl)methyloxy]anilinen-(4-chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinolinePazopanibPazopanib HCL3-Methyl-6-nitroindazole2,3-Dimethyl-6-nitro-2H-indazole2,3-Dimethyl-6-amino-2H-indazole2,3-Dimethyl-2H-indazol-6-amine hydrochlorideCeritinib2,5-Dichloro-N-[2-[(1-methylethyl)sulfonyl]phenyl]-4-pyrimidinamine5-Methyl-2-(1-methylethoxy)-4-(4-piperidinyl)benzenamine hydrochlorideTAK-438;Vonoprazan fumarate3-Pyridinesulfonyl chloride5-(2-Fluorophenyl)-1H-pyrrole-3-carboxaldehydeOlaparib(AZD2281)1-(Cyclopropylcarbonyl)piperazine hydrochlorideTAS 102Trifluorothymine6-(Chloromethyl)uracil3,4-Dihydro-2H-pyrrol-5-amine hydrochlorideLapatinibLapatinib ditosylate monohydrate3-Chloro-4-(3-fluorobenzyloxy)aniline4-Chloro-6-iodoquinazoline2-Aminoethylmethylsulfone hydrochlorideRociletinib(CO-1686)4-(4-Acetyl-1-piperazinyl)-2-(methyloxy)aniline(3-Aminophenyl)carbamic acid tert-butyl ester2,4-Dichloro-5-trifluoromethylpyrimidineRucaparibRucaparib camsylateRucaparib phosphate2-Bromo-8-fluoro-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one8-Fluoro-1,3,4,5-tetrahydro-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one6-Fluoro-1H-indole-4-carboxylic acid methyl estern-(2-oxoethyl)phthalimide5-Fluoro-2-methyl-3-nitrobenzoic acid methyl esterEzetimibeN-(4-(Benzyloxy)benzylidene)-4-fluoroaniline1-(Cyclopropylmethyl)piperazineN-(2,5-Dichlorobenzoyl)glycineABT-199 (GDC-0199)Venetoclax2-[(1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoic acid1-[[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazine3-Nitro-4-[[(tetrahydropyran-4-yl)methyl]amino]benzenesulfonamideMethyl 2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-fluorobenzoate1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexene-1-carboxaldehyde5-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridinetert-Butyl 4-bromo-2-fluorobenzoate4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde